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    Home»Technology & Startups»5 Best Ergonomic Mice (2025), Tested and Reviewed
    Technology & Startups

    5 Best Ergonomic Mice (2025), Tested and Reviewed

    November 11, 2025No Comments10 Mins Read0 Views
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    Other Ergonomic Mice to Consider

    There are several more options on the market to consider. These didn’t cut it as our top picks for one reason or another, but we still like them enough to recommend.

    Image may contain Computer Hardware Electronics Hardware and Mouse

    Razer Pro Click V2

    Photograph: Henri Robbins

    Razer Pro Click V2 for $120: The biggest draw of the Pro Click V2 (7/10, WIRED Recommends) is the shape: It’s sleek, refined, and comfortable. Instead of the sharp edges and angles of the Razer Basilisk, the Pro Click V2 has the curves of a normal mouse and is just as comfortable in an office setting as it would be in a gaming setup. And that’s what makes the Click stand out—you can use it everywhere, for everything. The shape is comfortable for regular use, the design is innocuous yet still satisfying, and the mouse has most of the usual trappings of a productivity mouse: An ergonomic shape, dual-mode mouse wheel, multidevice Bluetooth connectivity, and a slot on the underside to store the dongle. At the same time, it has the specs of a gaming mouse: 1,000-Hz polling, 2.4-GHz connectivity, full programmability, rubberized grips on either side, and bright RGB lighting on the underside. The Pro Click V2 also has horizontal scrolling through the mouse wheel, where it can be tilted to either side to scroll left and right. This isn’t quite as quick or intuitive as the MX Master’s thumb wheel, but it’s still nice to have. While it doesn’t match the Basilisk in performance, the Pro Click V2 is more affordable and a professional option that still has the sturdy build quality and responsive sensors Razer is known for.

    Logitech MX Master 3S a black computer mouse on top of a leather mousepad

    Logitech MX Master 3S

    Photograph: Julian Chokkattu

    Logitech MX Master 3S for $110: The previous-generation MX Master 3S is still worth considering if you can find it on sale for well below the MSRP or the price of the MX Master 4. You’re not missing a ton from the latest model, though the soft-touch plastic won’t look great after a few years of use (something the MX Master 4 addresses), and it doesn’t have the haptic-enabled Actions Ring. It’s still an excellent mouse and was previously the top pick in this guide.

    5 Best Ergonomic Mice  Tested and Reviewed

    Photograph: Henri Robbins

    Elecom Deft Pro for $65: Likely the best of Elecom’s offerings, the Deft Pro is a simple and robust trackball operated with your index finger (as opposed to your thumb). This allows for more precise movements, but isn’t quite as intuitive. I found it comfortable to use for extended periods, but I had a few hiccups—the scroll wheel is awkward to use with a thumb, and the right-click button (located on the far side of the ball) is thin. Still, the overall shape is comfortable once you’ve adapted to it.

    Contour Design Rollermouse Red Wireless for $394: This is a very niche and expensive product, but I was impressed by the build quality and usability. It is a wrist rest with an integrated mouse pad, operated using the cylinder at the top. You move the mouse left and right by sliding it along its rail, and up and down by rolling the cylinder forward and backward. It’s incredibly well made and shockingly smooth. A set of buttons sits underneath the spacebar, with dedicated copy/paste buttons, a double-click button, and adjustable sensitivity that beeps at you when you press the button. While the ergonomics feel unnatural at first, I quickly adapted to them and was able to navigate Windows easily within an hour or two of testing. However, as you would likely expect, any form of high-intensity gaming is out of the question: Halo CE felt less like a typical gaming experience and more like a challenge run with a drumset. The largest benefit of this device is that you can fully navigate your desktop without ever needing to remove your hands from the home row. It functions wonderfully and is a far more elegant solution than the trackpoint featured on keyboards like the HHKB Studio. With a high price and unconventional user experience, this is not for everyone. I struggle to say it’s worth the price. However, it’s specialized equipment, and these often tend to be expensive due to limited demand, high development costs, and low production numbers. If you’ve wanted something like this, I don’t think you’ll be disappointed.

    5 Best Ergonomic Mice  Tested and Reviewed

    Photograph: Henri Robbins

    Elecom Huge Trackball for $55: This trackball is … huge. It takes up a large amount of space on my desk and is intended to be used as a full-hand experience. You would expect a trackball branded as “Huge” to be intended for large hands, but the opposite seems to be true. There is a clear way this is meant to be used, and it is not compatible with larger hands. In my testing, when my hand was placed in the “correct” position (with my palm in the center and my wrist resting fully on the device), my thumb and fingers all extended past the buttons on the mouse, to the point that I could not reach the scroll wheel or back button. Moving my hand back, the functionality of the ergonomic shape was limited—it felt no more effective than using a smaller trackball. However, multiple people I asked with smaller hands report that it’s quite comfortable for them. I recommend purchasing from a site with a reasonable return policy. Build quality is solid, with the buttons feeling clicky and responsive; the ball has the slightest bit of stickiness before it gets moving. The ratcheting of the mouse wheel is subtle, but still present, and all the buttons are made from textured matte plastic that allows for some grip without being abrasive.

    5 Best Ergonomic Mice  Tested and Reviewed

    Photograph: Henri Robbins

    Elecom Rollermaster IST for $40: This is not a perfect trackball by any means, but for the price, it’s perfectly serviceable. The bearings are a bit loud, the materials don’t feel the most solid, but the functionality is all there, and the ergonomics are comfortable for a range of hand sizes. The trackball itself is easy to navigate, without any of the initial stickiness (sometimes called “stiction”) that some more premium models have—a trade-off for the louder operation of the ball. The roller bearings can also be easily removed and replaced with an included tool; however, a set of three replacement rollers is around half the price of the mouse at $18, and a set of the “upgraded” ball bearings is $25.

    Image may contain Computer Hardware Electronics Hardware and Mouse

    Keychron M6

    Photograph: Henri Robbins

    Keychron M6 for $70: If you like the design of the MX Master line, but would prefer a more gaming-oriented mouse, the Keychron M6 is a nice alternative. While the M6 doesn’t have Logitech’s advanced gesture controls or soft-touch exterior, it maintains the dual-mode scroll wheel, horizontal wheel, and general ergonomics while adding a 4,000-Hz refresh rate and shaving off almost half the weight of the 3S at only 78 grams. However, some small issues of build quality and a loss of functionality make this a less-than-ideal choice for most users—the dual-mode scroll wheel rattles during use, and the mouse feels lightweight to a fault. The higher-performance model’s wireless receiver requires a USB-C cable to connect to a device, which is a lot less convenient for laptop users compared to the low-profile dongle included with the 1,000-Hz model (and most other mice today).

    Image may contain Computer Hardware Electronics Hardware Mouse Computer Laptop and Pc

    Keychron M4

    Photograph: Henri Robbins

    Keychron M4 for $70: While you can realistically transport any of the mice on this list in a backpack or computer bag, I was impressed by just how compact the Keychron M4 is. I could easily slip it into a laptop bag or jacket pocket without any issue, and I even used it as a travel mouse for quite a while. While the shape isn’t great, or even good, ergonomically, I found the claw grip quite comfortable even during prolonged gaming sessions. However, it isn’t good enough that I would recommend it to anyone for daily use on a desktop setup unless they want the lightest mouse possible. The only real complaint I had with this mouse was the dongle: The 4,000-Hz model comes with a receiver shaped like a tiny keyboard with a USB-C port on the back, which meant I needed a cable to connect the receiver and a flat surface to place it on. Meanwhile, the 1,000-Hz model came with a simple USB dongle that could plug into the side of a laptop.

    Image may contain Computer Hardware Electronics Hardware and Mouse

    Logitech Pro X Superlight 2 Dex

    Courtesy of Logitech

    Logitech Pro X Superlight 2 Dex for $180: While this mouse is intended for high-intensity competitive gaming, I found its sculpted shape to be practical and comfortable for any long-term use, and its lightweight (60 grams!), no-frills design was quick and snappy for both spreadsheets and shooters. The mouse felt incredibly sturdy despite its weight, and the 8-kHz polling combined with a 44k-dpi sensor makes it the best-performing mouse on this list. While pricey, the Superlight DEX is a great single-mouse solution for someone who works from home and immediately starts queueing up after clocking out. It has a far more gaming-focused lean than the Razer Basilisk V3, which, while not bad, means you’re making a few more sacrifices to productivity in exchange for gaming performance.

    Image may contain Computer Hardware Electronics Hardware and Mouse

    Logitech MX Vertical

    Photograph: Henri Robbins

    Logitech MX Vertical for $120: While this mouse’s size and general shape both feel good for regular use, I found the shape to be a bit uncomfortable to fully grip and lift: A prominent ridge on the back dug into the space between my thumb and index finger, and the shape was just a bit too narrow to get a good hold on. However, the MX Vertical is still comfortable to hold with a looser grip, and it is perfectly serviceable for general office work and browsing, while putting less strain on the wrist than a standard horizontal mouse.

    Image may contain Computer Hardware Electronics Hardware and Mouse

    Logitech Lift

    Photograph: Henri Robbins

    Logitech Lift for $80: As one of the smaller vertical mice on this list, the Lift is just a bit too small. I found it difficult to comfortably grip this mouse for prolonged use, and friends with smaller hands found the same. That said, WIRED reviews editor Julian Chokkattu says his 5’2″ wife uses the Life and finds it perfect for her small hands, so your mileage will vary. Regardless of hand size, a larger vertical mouse is typically more comfortable for most people. It’s worth noting that the Lift is one of the only vertical mice I’ve tested with a left-handed configuration.

    Mice to Avoid

    5 Best Ergonomic Mice  Tested and Reviewed

    Photograph: Henri Robbins

    ProtoArc EM11 NL for $25: ProtoArc’s EM11 NL looks straight out of a sci-fi movie but falls short of real-world expectations. The sensor is a low-quality laser sensor that’s prone to jittering, and the underside of the mouse isn’t entirely flat—the sample I received wobbled like a chair with uneven legs. The shape of the mouse, while usable for smaller hands, is practically impossible to use comfortably with medium to large hands. The overall shape is too small to hold comfortably (the bottom of my hand dragged on the desk the entire time), and the flared section at the back, presumably meant to be a wrist rest, is far too angled to properly rest a hand on. There are some positive aspects to this mouse, like multi-device connectivity, a USB-A dongle, and adjustable sensitivity, but these struggle to make up for significant issues with build quality and ergonomics; issues I would argue are deal-breakers at any price.


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